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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf29923bfb9fc575c3ccc22a16902a72a34905b23688ab717b012a2ad5576d47' 
  AND token = 's6bV2HgkTEIyjs/lIKXEla0uLxP87OxCeTc4zywk15g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}