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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654c68d982a74b7d39a20c81df2cfe613cb5d28198e9b285b436f13616813abe' 
  AND token = '4qrTW/I9FUUQqL7XMLfB6IQnW0119JmA3ObitQN/yGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}