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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b8d1afea35a6214c16e7cd523ab5bfb775458d9eec153cfd1e58c95463989b8' 
  AND token = 'iM9pgEEPSmE11Di6HoQFl1Pxk+4oslsmxPA+EvuD/l8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}