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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f1400aa68de79621e94b2cd0d24646cb689ba1cfa00faf705fbeb4d3126ec69' 
  AND token = '8rS0ChfDdx6kme5/CtwJwbO0oClGsV1rSaRMQ72MJ8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}