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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a62917e30b37801cf8cc6c805d4a99a5b9baee6293a1f07057f87cd8a55750f' 
  AND token = '+6NPPcBcaJ0arRo0b/wEBo+d3RGN4tRf9igDIIFPfDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}