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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5d38645a6dc615f46a57f2b0e4a34ab1709b9f2db0e882da512d0c77b8e3491' 
  AND token = 'sfypYZQCpuT/H5RTGt6oxY3q3twmPnuxLnkZgyt3dPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}