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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b08fc23c5399a41757284a530174fb7115914338ed96f3d2fe42367f771b3be' 
  AND token = 'XEaaXut+gVelrpQ8QuW1m8AOXg0bFld34ga1EIQiCEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}