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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1b6c4096f66350f7328ba72b0d1bc4b56afcdf85f3f4726b1efee7c3a623a24' 
  AND token = '8vN4FsZF1eIIJbhlCIVaGi7Sx4mQd0rrUM/Z7E+h48g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}