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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80cd856f25b59af3eb51b1a24ba80f0ad709609e0d8dbf01f139fd5d0c330cf1' 
  AND token = 'ufXA97o/dbrInxfnR6/5T1aXSNxM92JeOPizy/4KcsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}