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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15e8861778d15d4c575e9ad41f12d56eeaf999c26057ffa0e19ae54b5b7c8bb0' 
  AND token = 'I2tSWnfQwmraJW7VvLMZWPG+44jeg+PZPMO1Ppmr/+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}