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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3c64177ee963aa1914319658138d4d9fb32150c7f91eb0f7e7f6de37765e5ce' 
  AND token = 'WHsAhrojCodAqX2QE/Md+dj78GuQ7QbZ3ng2ZM2EHcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}