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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dee0f8a863297a32b81e16cfe7695f60237a7549b20cbf7515906b4d311c667' 
  AND token = 'OdsdkoaJhQd1KVozBKYyZHrKX6fOopic3TBwbWXIN/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}