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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7d9896d60e75e953253e3fd453d383969096db398a4f52fe104a1ee65db655b' 
  AND token = '+YvSN/eIODyw2LqZRkNsE4TYRZ/pxSpOb8/2LfDFTEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}