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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa41d9f74e34f1bc84b6a62fbf63218a20ce1a2afb67ffc70e8e10ad0975d342' 
  AND token = 'zbOFtn973f/yFL7hNHpaxgCE/ZCWOnUXZWuo+5jaNoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}