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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28fea1271ee61df5748d23bf4d74c4ca07a59569bc4846f6bad5dea13e29ea0d' 
  AND token = 'kLUcK/mbT9vq/tGQBpMA5yi4BFXGRE4jC+oEq7Kli0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}