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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4afe666cc84345396b505cd165617468e690e7c8d1e9f23d26ccea5e3e1e9180' 
  AND token = 'jxIAUwsVIgE6LLNPZH3Gx53BRVwPwoJq3CYEUmFoJtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}