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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f245b5a2f729c47600bb7a70abc1abf1fc3ac3b0835951526b984da8b5c72fb9' 
  AND token = 'Wh1n+mrJgQEutv4hYBKSxBUuHnewk1ukoSdrN9cnjgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}