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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db81144ea9a4ee78ed44db293e76ed1278bae0137deb865b2d6afb9d03b157a0' 
  AND token = 'GQZt3STmwHadKjoy3EkKUQYE0PVzX2iVqrQ6FJSkbYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}