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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b7ce8b74d3aac31a9aa9fed9765dc9eca8b2d809bda97d7c030efd0f0b2d5f' 
  AND token = 'U2ciZpTXDhNiI9ReDrz7tx/mAjpsMW3sWTnWwmxv31Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}