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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dde1e378197ab167eb7766c0f9774c728054afcd966e6719a497d370e086454' 
  AND token = 'fch0/5qPs/qJhktcvdq/JhLhjJe8hFTBYMLKLlAX5MA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}