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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd142f4401cb95e81f1f4f3e95d5495ff7e9e1f2e01b46de56f9e53ae337de859' 
  AND token = 'I8PLkdWKkkInk4NSTNneRxWMqGGECh5CCgN1t5VuUa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}