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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5063162893464d6f70864b6e2eb1f2b82990f9eaec28272a292ad8c7d681f8a4' 
  AND token = 'Vv+Ft1e5uCz0T8FlSAuy3F2gGXXILLOAtbZXpC4nKNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}