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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e6c7d4b711768a973fef4ba134525a841785bca3a9f5084c5e7dc08d4e552c6' 
  AND token = '/k1KJ7Nak6EYs/ybC6XPEiHwP3o70mVyvL8zIrahZoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}