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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f49e1e38a57d2ed1b06c16e8c46a5efb5271ec0f627ceaa107913ca6d17a36b' 
  AND token = 'uOAPOx4o+mFmfoZy9CWAB6Qtd3Z6xlAukqMxt3waQOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}