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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3e3e6df88e8ad7d7aed16c840a47d8f6dcdae48250bd797ffad011a95f2facb' 
  AND token = 'ipyPkHf2M7zjrXfM1gaBx/k/Tj4qr1PF48J1kZMcsCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}