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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '991e43c34de02b311fc51a567414c61ee22a721e14a04e16d86fee9f5980f670' 
  AND token = 'A7v9Ng1/R38BkGHrYfb8hnq1xNGBZLK3Tbm58TUsXdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}