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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4357e1fbb0d3d4778a03bd94c41bfb5a34cac7cce290836c5a078748bcae1bcf' 
  AND token = '9fGwOgXLvd8SeFECHkfNNdQr17PDKH2t4/7iE+Ng3Do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}