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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c9b45bb03c3174848e90a2877c40a708fbbfd5e92cadad03b764662bdbecfe8' 
  AND token = 'UOpXfRJzLHnB3NoWWcX3EeJnIfX3MZ/+IsT7UnLvaAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}