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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6dada94b1266a7a656be03773432e6358f9d7e468e718c610ab49ae6365f54f' 
  AND token = '1Tiw2RNipbUkAO/oTg2yvcXbEOGvYoCEbHtuFdBSwYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}