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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a9eb31601030c46b4c43d322d3299be65dcc0adce9020e337c1fea422afb71b' 
  AND token = 'DJblmYWFg3Q3f62CkBfxYU8MicZjaLOPig2wS/xer2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}