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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422f5acba8b80d060d5fbd2d4ec43a431e6cd58e630c74a6cb35e1d09e8dd898' 
  AND token = 'ojEk4Rq7LCKz4MwTAuNuIl7djuYhtBTsEFSXBMM1kIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}