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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b3f593f58c21ba89da476509886eb61623d69b52c4ff703c397f904cb251256' 
  AND token = 't1A+vi88PEgDmgGGSg4G7NB3xWFfD1hRUDKIG6NZ6ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}