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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7976b0b095297d61630741fb53e225913dcbbbf141e835d051df27f3daffe477' 
  AND token = 'iiU6PUVeWoKD8noHXXsWPOoDs6LdcnZjYPo5nhg/mGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}