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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa77d31487eedb9ae642cc872c56d203bfb45b84842174a07d3e1e6d768f09d9' 
  AND token = 'ooI7kx2yj7QMQ3xLOazKaCPx2pFXKUhnAnjgN0Pwm9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}