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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d7af5ba7d25d1d60ff4c3c05dfc51a96d6b0b71f1dcd6f2f9458e0f97094490' 
  AND token = 'My48DmqDhdMjfiToL6qha0sdsDYQ4nDYyUqM5bQgmGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}