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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0ea26e60fc2b032ef37f90cfb895e245c42415106ff7691f58c63ce287726ab' 
  AND token = 'nYL8XYliPumGRztX8gipWP51j68r2FOW43Lc2dFudbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}