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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f4c9c44bdc56ec035c1f1205923e20f08290f2fc5a6d22ecfb2c5442d9ef4a4' 
  AND token = 'VsNQpk+GEYsW9jDkx5+orQ65We9RK3IZ1NlA12Jgpac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}