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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484e56b95f148c27624355b9281baea815c2509a18f12d51f2cbdb190551b2d7' 
  AND token = '41Ps9PylOQKDmOaKw+aQdcwl6BGM4U3L6zO0kE7ZuuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}