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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '074652506e971c702b528fd57476a8fd89afb6c4441fc06d43b646d66bf54b61' 
  AND token = 'SICu5w/H7j3ynf9lAJf5Zpr5EjKKsr7fAenjWe/sYhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}