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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ace06be4cb333055c3fef26ba0604865a7c5a887006a56ac7af2425f73b3dadd' 
  AND token = '+Yh0v7Gty3X2palP6FLgXd/MYLHrPMpC/pM86yWRx1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}