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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e9334dbdc0d03db702c8edfcc94f55f1c10485faa9fddfd4c23de018b86a570' 
  AND token = 'DGBK9IPPnqnKAQbcje7ZiovpCZ0J1bBX4QnQUxzbz0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}