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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f1da94a794584c4230677fe94efb4369a041b7771c7c462a32400e0e88365f6' 
  AND token = 'yoTNLT1HcKvqJpVKNTsEVhAf8aBcQjg2enRS26PbdXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}