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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a285afad7676a5db28af9b6e7ead337cbf7120c4fabfc3a313817fd162e8a6ed' 
  AND token = 'Ez3WXRga3kFutKTRsVuRYzabnwUYUPCwA6zUsgmsbQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}