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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46604e4a1d06e2469f8b7248c696f6f4ba2a13df9b0162e5a08fd39896de02f2' 
  AND token = 'nnen3g7JSk/j64ETbI6kD4csCI35KuMlFdDZ6fsnDEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}