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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb9358777e42429f5f0efc4ebfd7d6dd681c90fda9f4542f909831c5470740ce' 
  AND token = 'sCAB8OMzyRv4HwGk3u+v2tfjXvrqtepMX/7Ys0SaBpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}