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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '399478777f559f3c7a2df0e362357e9c4dc299ddba59064d61c0417edd9da2c0' 
  AND token = 'h5H6iaQQU/T/eV/3E398OFnNyy5ZPpWNM1q4KCEgb3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}