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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66d601adaa19b3b04d12f8142172f25dd54208c0e9aa48a1146b2b84bba916ec' 
  AND token = 'x2c9m6TZx5ODMr5F9XTBhMc80+Hypp+0otQBhFx7ys4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}