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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39465c298068a245f2b65f8d5a29bc12d034ab6164bf2a463e644a84f500be3e' 
  AND token = '3AhuahCAQ6psztw9KMH6zjAG9z8VayVv7pyVibfIg4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}