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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3619ee88ce75323a9372142dd9766f7e29c62c89c29d766fa8267285b1e2d16' 
  AND token = 'drjsvUP5Cms6VlmYpQz+So+nmEeq+dOJG6k2MEQtN/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}