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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aee7291e3f3a701121e0788a5b9433524115a27af0db57909b428391638fe303' 
  AND token = 'Io7DCgZRmLsRuUR1Xl3hH81wGqHgwZo2re5gR0riUuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}